Developing Fully Degradable Polymeric Cryoprotectants at the University of Manchester
Developing Fully Degradable Polymeric Cryoprotectants at the University of Manchester
GibsonGroup, University of Manchester soliciting applications for a PhD to design and develop completely degradable polymeric cryoprotectants. Extremophiles are organisms that operate under the most extreme temperatures, and to survive within such environment, they produce specific proteins-which include antifreeze and ice-nucleating proteins. Such, however, have many practical disadvantages: they are many times expensive to produce on a large scale and sometimes present toxic or immunogenic properties.
GibsonGroup has identified Macromolecular
Cryoprotectants—artificial polymers that control ice formation and accretion. Already these materials are finding uses in the cryopreservation of advanced pharmaceuticals including antibodies, biological tissues - blood and stem cells, and animal-free testing for toxicity within the biotechnology arena. They will find utility in resolving ice-related problems associated with frozen food and transport infrastructure. Relevant articles: Nature Communications (2017), ACS Applied Materials & Interfaces (2023), and Biomacromolecules (2022).
PhD Focus
Synthesis of fully degradable polymeric cryoprotectants which are meant to be applied in vivo and at the same time more environmentally friendly. Research in this project would focus more on sustainability as well, using feedstocks sourced from biological origins for the preparation of these novel materials. Activities would involve synthesizing polymers and exposure to different kinds of cryo-biology and microscopy techniques to verify the materials produced.
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Research Environment
The GibsonGroup is based in the state-of-the-art laboratories of the Department of Chemistry and the Manchester Institute of Biotechnology. The group accommodates highly specialized facilities for organic and polymer synthesis, cell culture, microbiology, and advanced imaging: confocal microscopy, to name but a few options true multidisciplinary approach to solving some of the planet's greatest challenges.
To find out more, please visit the GibsonGroup website: Gibson Group Research.
Entry Requirements
Interested applicants are expected to possess at least an honours degree with a 2.1 classification, or a Master's degree (or international equivalent) in a relevant science or engineering discipline.
Be part of cutting-edge research on the interfaces between polymer chemistry, cryobiology, and sustainability!
How to Apply:
Apply to this PhD opportunity at the University of Manchester by following these application steps:
Click here to access the application portal: PhD Application Portal.
Documents to Obtain:
You will need to have the following documents ready:
Personal Statement: Explain why you want to undertake this PhD and how your background matches the research scope
Transcripts: Transcript of the previous degrees undergraduate and master's, if taken
CV/Resume: Relevant experience at a level equivalent to a medical laboratory science degree or higher in either of the relevant science or engineering disciplines.
References: Names and contact details of two academic referees, who may provide support to the application
Proof of English Language Proficiency: If necessary attach a copy of the IELTS or TOEFL score. This depends on the nationality and previous studies done.
Complete the online application form
Personal Information
Academic Qualifications
Interests and Objectives
Attach all attached documents
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Apply for Application:
Ensure that all entries are accurate and that one makes a tour online portal to submit the application.
If you have further questions, you may visit our University of Manchester website application guidance pages or contact the admissions office and they will be able to assist you further.
Apply now for this research degree in polymeric cryoprotectants and join us in creating the path forward for truly groundbreaking research!
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If there is any doubt, he can ask me